Detalhe da pesquisa
1.
Norspermidine is not a self-produced trigger for biofilm disassembly.
Cell
; 156(4): 844-54, 2014 Feb 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-24529384
2.
Cyclin-dependent kinase 12 is a drug target for visceral leishmaniasis.
Nature
; 560(7717): 192-197, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30046105
3.
Author Correction: Cyclin-dependent kinase 12 is a drug target for visceral leishmaniasis.
Nature
; 619(7970): E48, 2023 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-37402863
4.
Oligo targeting for profiling drug resistance mutations in the parasitic trypanosomatids.
Nucleic Acids Res
; 50(14): e79, 2022 08 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35524555
5.
Antileishmanial Activities of (Z)-2-(Nitroimidazolylmethylene)-3(2H)-Benzofuranones: Synthesis, In Vitro Assessment, and Bioactivation by NTR 1 and 2.
Antimicrob Agents Chemother
; 66(11): e0058322, 2022 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36286539
6.
High-Throughput Screening Platform To Identify Inhibitors of Protein Synthesis with Potential for the Treatment of Malaria.
Antimicrob Agents Chemother
; 66(6): e0023722, 2022 06 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-35647647
7.
Identification of a Proteasome-Targeting Arylsulfonamide with Potential for the Treatment of Chagas' Disease.
Antimicrob Agents Chemother
; 66(1): e0153521, 2022 01 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34606338
8.
Preclinical candidate for the treatment of visceral leishmaniasis that acts through proteasome inhibition.
Proc Natl Acad Sci U S A
; 116(19): 9318-9323, 2019 05 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30962368
9.
Clinical and veterinary trypanocidal benzoxaboroles target CPSF3.
Proc Natl Acad Sci U S A
; 115(38): 9616-9621, 2018 09 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-30185555
10.
Antitrypanosomal 8-Hydroxy-Naphthyridines Are Chelators of Divalent Transition Metals.
Antimicrob Agents Chemother
; 62(8)2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29844044
11.
Activation of Bicyclic Nitro-drugs by a Novel Nitroreductase (NTR2) in Leishmania.
PLoS Pathog
; 12(11): e1005971, 2016 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-27812217
12.
Snapshot Profiling of the Antileishmanial Potency of Lead Compounds and Drug Candidates against Intracellular Leishmania donovani Amastigotes, with a Focus on Human-Derived Host Cells.
Antimicrob Agents Chemother
; 61(3)2017 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28069646
13.
TrypanoCyc: a community-led biochemical pathways database for Trypanosoma brucei.
Nucleic Acids Res
; 43(Database issue): D637-44, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25300491
14.
Homoserine and quorum-sensing acyl homoserine lactones as alternative sources of threonine: a potential role for homoserine kinase in insect-stage Trypanosoma brucei.
Mol Microbiol
; 95(1): 143-56, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25367138
15.
Arsenic, antimony, and Leishmania: has arsenic contamination of drinking water in India led to treatment- resistant kala-azar?
Lancet
; 385 Suppl 1: S80, 2015 Feb 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-26312902
16.
Nitroheterocyclic drug resistance mechanisms in Trypanosoma brucei.
J Antimicrob Chemother
; 71(3): 625-34, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26581221
17.
Pentacyclic nitrofurans that rapidly kill nifurtimox-resistant trypanosomes.
J Antimicrob Chemother
; 71(4): 956-63, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26682963
18.
Chronic exposure to arsenic in drinking water can lead to resistance to antimonial drugs in a mouse model of visceral leishmaniasis.
Proc Natl Acad Sci U S A
; 110(49): 19932-7, 2013 Dec 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-24167266
19.
Biochemical and genetic characterization of Trypanosoma cruzi N-myristoyltransferase.
Biochem J
; 459(2): 323-32, 2014 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24444291
20.
Allosteric activation of trypanosomatid deoxyhypusine synthase by a catalytically dead paralog.
J Biol Chem
; 288(21): 15256-67, 2013 May 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-23525104